BIO BIOINFORMATICS BASICS UG
Unit I |
Overview of Bioinformatics |
Scope |
Application |
History |
Resources |
NCBI |
EBI |
ExPasy |
Introduction to Biological
Database. |
Types of Biological
databases |
Nucleotide Sequence
Databases |
Genbank |
DDBJ |
EMBL |
Protein Sequence Databases |
Swissprot |
TrEMBL |
Protein Structure Database |
PDB |
Derived Databases |
Prosite |
Pfam |
Literature Databases |
Pubmed |
OMIM |
Unit II |
Sequence analysis |
Sequence alignment methods |
Pairwise sequence
alignments |
BLAST |
FASTA |
Multiple sequence
alignment |
Clustal X |
Phylogenetic analysis |
Unit III |
Protein Secondary
structure prediction |
Use of sequence pattern |
Leucine zipper |
Coiled coil |
Transmembrane |
signal peptide |
cleavage site Chou-Fasman |
Unit IV |
Protein Structure
Prediction |
Prediction of 3D
structures by comparative modeling |
Homology modeling |
fold recognition by
threading |
ab-initio prediction |
Protein Visualisation
Tools-Rasmol |
Protein Visualisation
Tools - SwisspdbViewer |
Unit V |
Introduction to Genomics |
Types
of Genomics |
Functional Genomics |
Structural and Comparative
Genomics |
Structural and Comparative
Genomics |
Map Viewer |
Genome database |
GOLD Database |
Metabolic Pathway Database |
KEGG |